Dendritic cells in hair loss due to alopecia areata

Dermatologica. 1985;171(5):327

Increased number of OKT6-positive dendritic cells in the hair follicles of patients with alopecia areata.

Kohchiyama A, et al

edited
In 6 patients with untreated hair loss secondary to alopecia areata in the progressive stage, 6 in the stationary stage, and 6 normal individuals as controls, an in situ analysis of OKT6-positive dendritic cells in hair follicles, and peribulbar and intrabulbar infiltrates was performed using the avidin-biotin-peroxidase method with monoclonal antibodies. …snip… This indicates that the number of OKT6-positive dendritic cells increases in the hair follicles of progressive alopecia areata and that these cells may play an important role in cooperation with T cells in the pathogenesis of alopecia areata.

Leave a Reply